Cytoscape Web
Click node...

Narcolepsy-cataplexy
7 OMIM references -
8 associated genes
10 signs/symptoms
PROTEIN INTERACTIONS: 1
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type
1 OMIM reference -
1 associated gene
13 signs/symptoms
Narcolepsy-cataplexy
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type

CTSH
(UniProt - OMIM)
 APP
(UniProt - OMIM)
HCRT
(UniProt - OMIM)
HLA-DQB1
(UniProt - OMIM)
HLA-DRB1
(UniProt - OMIM)
MOG
(UniProt - OMIM)
P2RY11
(UniProt - OMIM)
TNFSF4
(UniProt - OMIM)
ZNF365
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
ZNF365
(0.56)
APP


Citations in the biomedical literature:


Narcolepsy-cataplexy
CTSH HCRT HLA-DQB1 HLA-DRB1 MOG P2RY11
TNFSF4 ZNF365
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type
APP



Narcolepsy-cataplexy
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type

Synonym(s):
- Gélineau disease
Synonym(s):
- HCHWA, Piedmont type
Classification (Orphanet):
- Rare neurologic disease
Classification (Orphanet):
- Rare genetic disease
- Rare neurologic disease
- Rare systemic or rheumatologic disease
Classification (ICD10):
- Diseases of the nervous system -
Classification (ICD10):
(no data available)
Epidemiological data:
Class of prevalence: 1-5 / 10 000
Average age onset: adolescence / young
Average age of death: normal
Type of inheritance: unknown
Epidemiological data:
(no data available)
External references:
7 OMIM references -
1 MeSH reference: D009290
External references:
1 OMIM reference -
No MeSH references
Narcolepsy-cataplexy
Hereditary cerebral hemorrhage with amyloidosis, Piedmont type

Very frequent
- Delirium / hallucination
- Muscle weakness / flaccidity
- Sleep and vigilance disorders
- Somnolence / hypersomnia / parasomnia
- Troubles of memory / amnesia / hypermnesia

Frequent
- Abnormal eye movements / oculomotor disorder
- Anomalies of eyes and vision

Occasional
- Collapse / sudden death / cardiac arrest / cardiorespiratory arrest
- Generalized obesity
- Speech troubles / aphasia / dysphasia / echolalia / mutism / logorrhea / dysprosodia


Very frequent
- Autosomal dominant inheritance
- Intellectual deficit / mental / psychomotor retardation / learning disability
- Intracranial / cerebral / meningeal hemorrhage
- Motor deficit / trouble
- Obnubilation / coma / lethargia / desorientation
- Paresthesia / dysesthesia / hypoesthesia / anesthesia / numbness
- Psychic / psychomotor regression / dementia / intellectual decline
- Sensitive trouble / deficit
- Transient cerebral ischemia / stroke

Frequent
- Cerebral vascular anomalies
- Facial pain / cephalalgia / migraine
- Psychic / behavioural troubles

Occasional
- Early death / lethality